首页

孙红宾

时间:2018-07-26浏览:1097设置


孙红宾,博士,教授,硕士生导师。2007年毕业于中国科学技术大学生命科学学院生物化学与分子生物学专业,获博士学位;2007年至2009年在美国德州大学西南医学中心药学系从事博士后研究工作;2009年至2018年,在中科院强磁场科学中心工作,先后担任副研究员、研究员,硕士生导师。

主要研究方向为应用核磁共振研究微生物相关蛋白质的结构与功能,抗菌肽的抗菌机制。

近年来,在ACS NanoPNASBBAScience等学术杂志上发表论文二十余篇。先后主持与参与了国家自然科学基金青年基金、面上项目,国家自然科学基金大科学装置联合基金培育项目、重点项目等。

代表性论文:

1.Shanhui Liao, Hongbin Sun#, Chao Xu#. YTH Domain: A Family of N6-methyladenosine (m6A) Readers. Genomics Proteomics Bioinformatics. (2018) 16(2):99-107 (#co-corresponding author)

2.Yue Yuan, Shuchao Ge, Hongbin Sun,Xuejiao Dong, Hongxin Zhao, Linna An, Jia Zhang, Junfeng Wang, Bing Hu and Gaolin Liang. Intracellular Self-Assembly and Disassembly of 19F Nanoparticles Confer Respective Off and On 19F NMR/MRI Signals for Legumain Activity Detection in Zebrafish. ACS Nano. (2015) 9(5):5117-5124.

3.Fazhan Shi*, Qi Zhang*, Pengfei Wang*, Hongbin Sun, Jiarong Wang, Xing Rong, Ming Chen, Chenyong Ju, Friedemann Reinhard, Hongwei Chen, Jörg Wrachtrup, Junfeng Wang, Jiangfeng Du. Single-protein spin resonance spectroscopy under ambient conditions. Science. (2015) 347:1135-8. (*co-first author)

4.Yue Yuan*,Hongbin Sun*,Shuchao Ge*,Mengjing Wang,Hongxin Zhao,Lin Wang,Linna An,Jia Zhang,Huafeng Zhang, Bing Hu, Junfeng Wang, and Gaolin Liang. Controlled Intracellular Self-Assembly and Disassembly of 19F Nanoparticles for MR Imaging of Caspase 3/7 in Zebrafish. ACS Nano. (2015) 27:761-8. (*co-first author)

5.Jiarong Wang, Yan Li, Xiaoming Wang, Wei Chen, Hongbin Sun#, Junfeng Wang#. Lipopolysaccharide induces amyloid formation of antimicrobial peptide HAL-2. Biochim Biophys Acta. 2014 Nov;1838(11):2910-8. (#co-corresponding author)

6.Soonjoung Kim*, Hongbin Sun*, Diana R. Tomchick, Hongtao Yu, and Xuelian Luo. Structure of Human Mad1 C-terminal Domain Reveals Its Involvement in Kinetochore Targeting. PNAS, (2012) 109:6549-54. (*co-first author) 

7.Soonjoung Kim, Hongbin Sun, Haydn L. Ball, Katja Wassmann, Xuelian Luo, and Hongtao Yu, Phosphorylation of the spindle checkpoint proteinMad2 regulates its conformational transition, PNAS, (2010) 107:19772-19777

8.Xiaowei Zhang, Xiaojing Yan, Ziren Zhou, Feifei Yang, Ziyu Wu, Hongbin Sun, Wenxue Liang, Aixin Song, Valérie Lallemand-Breitenbach, Marion Jeanne, Qunye Zhang, Huaiyu Yang, Qiuhua Huang, Guangbiao Zhou, Jianhua Tong, Yan Zhang, Jihui Wu, Hongyu Hu, Hugues de Thé, Saijuan Chen, Zhu Chen. Arsenic trioxide controls the fate of the PML-RARalpha oncoprotein by directly binding PML. Science, (2010) 328(5975):240-3

9.Hongbin Sun, Jiangxin Liu, Jiahai Zhang, Hongda Huang, Haiming Dai, Chao xu, Jihui Wu, and Yunyu Shi. Solution Structure of the Bromodomain of BRD7 and Its Association with Acetylated Peptide. Biochem. Biophys. Res. Commun. (2007) 358:435-441.

10.Hongbin Sun, Haiming Dai, Jiahai Zhang, Shangmin Xiong, Jian Xu, Jihui Wu, and Yunyu Shi. Solution Structure of Calponin Homology Domain of Human MICAL-1. Journal of Biomolecular NMR. (2006) 36:295–300.



返回原图
/